WebHowever, enhancement of SMAD1/5/9 phosphorylation was observed in CD109 knockdown cells under bone morphogenetic protein-2 (BMP-2) stimulation. We also performed immunohistochemical analysis for phospho-SMAD1/5/9 using human osteosarcoma tissue and found a negative correlation between CD109 expression and SMAD1/5/9 … WebMutations in SMAD9 gene encoding for transforming growth factor (TGF)- [beta] superfamily have been identified in Pulmonary Arterial Hypertension. Phosphorylated Smad1/5/8/9 specifically bound to the BREs of Smad8/9 gene. The present study reveals that Smad8/9 is a unique R-Smad regulated through the BMP pathway at the mRNA level.
Anti-phospho Smad1/Smad5/Smad8 (Ser463/465) AB3848-I
WebSMADs can be divided into receptor-regulated SMADs, common-mediator SMAD and inhibitory SMADs. SMAD1, SMAD5 and SMAD9 have high degrees of homology. SMAD8 … Websurrounding Ser190 of human Smad1, Asp165 of human SMAD4, or Pro249 of human Smad5 protein. 3 Products Included Product # Quantity Mol. Wt. Isotype Phospho-Smad1 (Ser206) (D40B7) Rabbit mAb 5753 20 µl 60 kDa Rabbit IgG Phospho-Smad1/5 (Ser463/465) (41D10) Rabbit mAb 9516 20 µl 60 kDa Rabbit IgG Phospho-Smad1 (Ser463/465)/ Smad5 … black acres
Smad1 (Phospho Ser214) rabbit pAb-博奥龙Biodragon
WebOct 10, 2024 · Hepcidin, a major regulator of systemic iron homeostasis, is mainly induced in hepatocytes by activating bone morphogenetic protein 6 (BMP-6) signaling in response to changes in the iron status. Small heterodimer partner-interacting leucine zipper protein (SMILE), a polyphenol-inducible transcriptional co-repressor, regulates hepatic … WebPhospho-Smad1/5 (Ser463, Ser465) Antibody (BS-3418R) in WB. Lane 1: Mouse Lymph node lysates; Lane 2: Mouse Uterus lysates probed with Smad1/5 (Ser463 + Ser465) Polyclonal Antibody, Unconjugated (bs-3418R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C. WebThe Phospho-Smad1 (Ser463/465)/ Smad5 (Ser463/465)/ Smad9 (Ser465/467) (D5B10) Rabbit mAb Antibody has been validated for the following applications: Precipitation, Flow … dauntless faction symbol