WebMar 1, 2013 · Yeast Pah1p phosphatidate phosphatase (PAP) catalyzes the penultimate step in the synthesis of triacylglycerol. PAP plays a crucial role in lipid homeostasis by controlling the relative proportions of its substrate phosphatidate and … WebPhosphatidic acid (PA) phosphatase is an evolutionarily conserved enzyme that plays a major role in lipid homeostasis by controlling the cellular levels of its substrate, PA, and …
Relationship of glucose and oleate metabolism to cardiac function …
WebApr 14, 2024 · The LPP family is comprised of three enzymes that dephosphorylate bioactive lipid phosphates both intracellularly and extracellularly. Pre-clinical breast cancer models have demonstrated that decreased LPP1/3 with increased LPP2 expression correlates to tumorigenesis. This though has not been well verified in human specimens. In this study, … WebMagnesium-dependent phosphatidate phosphatase which catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol. Acts redundantly with PAH2 to repress … grand ole opry scotty mccreery
Phosphatidic acid - Wikipedia
WebSep 27, 2010 · Lipins, a novel family of phosphatidate (PA) phosphatases that generate diacylglycerol (DAG) from PA, are emerging as essential regulators of fat metabolism, adipogenesis, and organelle biogenesis. The mechanisms that govern lipin translocation onto membranes are largely unknown. WebApr 1, 2024 · Pah1 phosphatidate phosphatase and Dgk1 diacylglycerol kinase are key players that function counteractively in the control of the phosphatidate level at the nuclear/endoplasmic reticulum membrane. WebPhosphatidate Phosphatase QU 136. Connect with NLM. National Library of Medicine 8600 Rockville Pike Bethesda, MD 20894 . Web Policies FOIA HHS Vulnerability Disclosure. NLM Support Center Accessibility Careers . grand ole opry schedule of performers 2014