Chimeric lysin
WebNov 28, 2024 · Scientific Reports - Csl2, a novel chimeric bacteriophage lysin to fight infections caused by Streptococcus suis, an emerging zoonotic pathogen Skip to main … WebSep 15, 2014 · Developing chimeric lysins with a wide lytic spectrum would be important for treating some infections caused by multiple pathogenic bacteria. In the present work, a novel chimeric lysin (Ply187N-V12C) …
Chimeric lysin
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WebMay 25, 2024 · A newly evolved chimeric lysin motif receptor-like kinase in Medicago truncatula spp. tricycla R108 extends its Rhizobia symbiotic partnership. ... Using genomics and reverse genetics, we identified a newly evolved, chimeric LysM receptor-like kinase gene in R108, LYK2bis, ... WebMar 29, 2024 · Chimeric lysin candidates were created through fusion with various enzymatic and cell-wall-binding domains based on LysK lysin, autolysins and lysostaphin …
WebFeb 10, 2024 · The control was performed without chimeric lysin. (A) Changes in total viable counts in the chilled chicken during storage at 4 °C for 14 days. (B) Changes in the pH of the chilled chicken during ... WebSep 15, 2014 · In the present work, a novel chimeric lysin (Ply187N-V12C) was constructed by fusing Ply187N with the CBD (146-314aa, V12C) of PlyV12 to test if the lytic specificity of Ply187N would be extended to …
WebIn this study, we evaluated the anti-biofilm and anti-demineralization abilities of a novel material, CMC-ClyR-ACP nanogel, designed by loading the chimeric lysin ClyR and amorphous calcium phosphate (ACP) into a nanocarrier material carboxymethyl chitosan (CMC), in a demineralization model. WebSep 4, 2024 · On the contrary, the addition of a CPP to LysK or the chimeric lysin L-K did not result in enhanced intracellular killing. Surprisingly, the chimeric lysin K-L already had the capacity to kill intracellular S. aureus without a CPP. In a next step, Becker and colleagues tested the efficacy of their approach in a murine mastitis model.
WebFeb 1, 2024 · Chimeric ClyV lysin (obtained by fusion of the enzymatically active domain from PlyGBS lysin and the cell wall binding domain from PlyV12 lysin) presented improved bactericidal activity in vitro ...
WebApr 17, 2014 · The chimeric lysin (called ClyS) was obtained by fusing the N-terminal catalytic domain of the S. aureus Twort phage lysin with the C-terminal cell wall-targeting domain from another S. aureus ... phillipa hurrellWebLysin definition, an antibody causing the disintegration of erythrocytes or bacterial cells. See more. try logging guild lost arkWebApr 19, 2024 · In this study, a novel chimeric lysin, ClyC, was constructed by fusing the CD from the Ply187 lysin with the CBD from the LysSA97 lysin. The CD of Ply187 … trylolliWebJan 9, 2024 · Yang, H. et al. Novel chimeric lysin with high-level antimicrobial activity against methicillin-resistant Staphylococcus aureus in vitro and in vivo. Antimicrob. Agents Chemother. 58 , 536–542 ... phillip aireyWebNov 16, 2024 · Cationic peptide chimeric lysins, Lysqdvp001-5aa, Lysqdvp001-10aa and Lysqdvp001-15aa, were designed based on lysin Lysqdvp001 from Vibrio parahaemolyticus (V. parahaemolyticus) phage qdvp001.These chimeric lysins showed equivalent peptidoglycan hydrolysis activities with Lysqdvp001 and could lyse the bacteria from the … trylock c#WebMay 29, 2024 · The chimeric lysin, ClyR, was expressed in E. coli BL21(DE3), purified through Ni-nitrilotriacetic acid affinity chromatography and dialyzed against phosphate-buffered saline (PBS, containing 137 mM NaCl, 2.7 mM KCl, 10 mM Na 2 HPO 4, 2 mM KH 2 PO 4, pH 7.4) as described previously . 2.2. In Vitro Lytic Activity Assay. trylon apartmentsWebNov 16, 2024 · Cationic peptide chimeric lysins, Lysqdvp001-5aa, Lysqdvp001-10aa and Lysqdvp001-15aa, were designed based on lysin Lysqdvp001 from Vibrio … phillipa lepley baby olivia